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N-methyl-D-aspartate receptor inhibition by an apolipoprotein E-derived peptide relies on low-density lipoprotein receptor-associated protein

The effects of a synthetic apoE peptide, viz., residues 133–149 (apoE[133–149]), a mimetic that comprises the apoE receptor-binding domain, on N-methyl-D-aspartate (NMDA)/glycine-induced ion flow through NMDA receptor (NMDAR) channels, has been investigated. The activity of apoE[133–149] was found t...

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Main Authors: Sheng, Zhenyu, Prorok, Mary, Brown, Brigid E., Castellino, Francis J.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2610414/
https://ncbi.nlm.nih.gov/pubmed/18602124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2008.05.016
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