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Ca(2+)-induced self-assembly in designed peptides with optimally spaced gamma-carboxyglutamic acid residues
We have previously elucidated a new paradigm for the metal ion-induced helix-helix assembly in the natural γ-carboxyglutamic acid (Gla)-containing class of conantokin (con) peptides, typified by con-G and a variant of con-T, con-T[K7Gla]. independent of the hydrophobic effect. In these “metallo-zipp...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3662978/ https://ncbi.nlm.nih.gov/pubmed/21134602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2010.10.002 |
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