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Ca(2+)-induced self-assembly in designed peptides with optimally spaced gamma-carboxyglutamic acid residues

We have previously elucidated a new paradigm for the metal ion-induced helix-helix assembly in the natural γ-carboxyglutamic acid (Gla)-containing class of conantokin (con) peptides, typified by con-G and a variant of con-T, con-T[K7Gla]. independent of the hydrophobic effect. In these “metallo-zipp...

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Autores principales: Dai, Qiuyun, Dong, Mingxin, Liu, Zhuguo, Prorok, Mary, Castellino, Francis J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662978/
https://ncbi.nlm.nih.gov/pubmed/21134602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2010.10.002
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