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Valproic acid influences the expression of genes implicated with hyperglycaemia-induced complement and coagulation pathways

Because the liver plays a major role in metabolic homeostasis and secretion of clotting factors and inflammatory innate immune proteins, there is interest in understanding the mechanisms of hepatic cell activation under hyperglycaemia and whether this can be attenuated pharmacologically. We have pre...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Felisbino, Marina Barreto, Ziemann, Mark, Khurana, Ishant, Okabe, Jun, Al-Hasani, Keith, Maxwell, Scott, Harikrishnan, K. N., de Oliveira, Camila Borges Martins, Mello, Maria Luiza S., El-Osta, Assam
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2021
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7835211/
https://ncbi.nlm.nih.gov/pubmed/33495488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81794-4
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