Epigenetic evidence of an Ac/Dc axis by VPA and SAHA

BACKGROUND: Valproic acid (VPA) is one of the most commonly used anti-epileptic drugs with pharmacological actions on GABA and blocking voltage-gated ion channels. VPA also inhibits histone deacetylase (HDAC) activity. Suberoylanilide hydroxamic acid is also a member of a larger class of compounds t...

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Publicat a:Clin Epigenetics
Autors principals: Lunke, Sebastian, Maxwell, Scott, Khurana, Ishant, K.N., Harikrishnan, Okabe, Jun, Al-Hasani, Keith, El-Osta, Assam
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7981901/
https://ncbi.nlm.nih.gov/pubmed/33743782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-021-01050-4
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