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DNA methylation status correlates with adult β-cell regeneration capacity
The role of DNA methylation in β-cell neogenesis is poorly understood. We report that during the process of induced cell reprogramming, methylation content of the Ngn3 and Sox11 genes are diminished. These findings emphasise DNA methylation is a barrier in β-cell regeneration in adulthood, a well de...
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| Publicado no: | NPJ Regen Med |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7881134/ https://ncbi.nlm.nih.gov/pubmed/33580013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41536-021-00119-1 |
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