Sex-Based Mhrt Methylation Chromatinizes MeCP2 in the Heart

In the heart, primary microRNA-208b (pri-miR-208b) and Myheart (Mhrt) are long non-coding RNAs (lncRNAs) encoded by the cardiac myosin heavy chain genes. Although preclinical studies have shown that lncRNAs regulate gene expression and are protective for pathological hypertrophy, the mechanism under...

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Publicado no:iScience
Main Authors: K.N., Harikrishnan, Okabe, Jun, Mathiyalagan, Prabhu, Khan, Abdul Waheed, Jadaan, Sameer A., Sarila, Gulcan, Ziemann, Mark, Khurana, Ishant, Maxwell, Scott S., Du, Xiao-Jun, El-Osta, Assam
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639684/
https://ncbi.nlm.nih.gov/pubmed/31323475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2019.06.031
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