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Key interplay between the co-opted sorting nexin-BAR proteins and PI3P phosphoinositide in the formation of the tombusvirus replicase

Positive-strand RNA viruses replicate in host cells by forming large viral replication organelles, which harbor numerous membrane-bound viral replicase complexes (VRCs). In spite of its essential role in viral replication, the biogenesis of the VRCs is not fully understood. The authors identified cr...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Feng, Zhike, Kovalev, Nikolay, Nagy, Peter D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7833164/
https://ncbi.nlm.nih.gov/pubmed/33370420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1009120
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