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Role of Viral RNA and Co-opted Cellular ESCRT-I and ESCRT-III Factors in Formation of Tombusvirus Spherules Harboring the Tombusvirus Replicase

Plus-stranded RNA viruses induce membrane deformations in infected cells in order to build viral replication complexes (VRCs). Tomato bushy stunt virus (TBSV) co-opts cellular ESCRT (endosomal sorting complexes required for transport) proteins to induce the formation of vesicle (spherule)-like struc...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Kovalev, Nikolay, de Castro Martín, Isabel Fernández, Pogany, Judit, Barajas, Daniel, Pathak, Kunj, Risco, Cristina, Nagy, Peter D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4794697/
https://ncbi.nlm.nih.gov/pubmed/26792735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02775-15
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