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Recruitment of Vps34 PI3K and enrichment of PI3P phosphoinositide in the viral replication compartment is crucial for replication of a positive-strand RNA virus

Tombusviruses depend on subversions of multiple host factors and retarget cellular pathways to support viral replication. In this work, we demonstrate that tomato bushy stunt virus (TBSV) and the closely-related carnation Italian ringspot virus (CIRV) recruit the cellular Vps34 phosphatidylinositol...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS Pathog
Päätekijät: Feng, Zhike, Xu, Kai, Kovalev, Nikolay, Nagy, Peter D.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6342326/
https://ncbi.nlm.nih.gov/pubmed/30625229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007530
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