Co-opted Cellular Sac1 Lipid Phosphatase and PI(4)P Phosphoinositide Are Key Host Factors during the Biogenesis of the Tombusvirus Replication Compartment

Positive-strand RNA [(+)RNA] viruses assemble numerous membrane-bound viral replicase complexes (VRCs) with the help of viral replication proteins and co-opted host proteins within large viral replication compartments in the cytosol of infected cells. In this study, we found that deletion or depleti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Virol
Prif Awduron: Sasvari, Zsuzsanna, Lin, Wenwu, Inaba, Jun-Ichi, Xu, Kai, Kovalev, Nikolay, Nagy, Peter D.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2020
Pynciau:
Virus-Cell Interactions
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307105/
https://ncbi.nlm.nih.gov/pubmed/32269127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01979-19
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg