Co-opted Cellular Sac1 Lipid Phosphatase and PI(4)P Phosphoinositide Are Key Host Factors during the Biogenesis of the Tombusvirus Replication Compartment

Positive-strand RNA [(+)RNA] viruses assemble numerous membrane-bound viral replicase complexes (VRCs) with the help of viral replication proteins and co-opted host proteins within large viral replication compartments in the cytosol of infected cells. In this study, we found that deletion or depleti...

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Sasvari, Zsuzsanna, Lin, Wenwu, Inaba, Jun-Ichi, Xu, Kai, Kovalev, Nikolay, Nagy, Peter D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2020
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7307105/
https://ncbi.nlm.nih.gov/pubmed/32269127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01979-19
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