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ASK1 Regulates Immune-Mediated Thrombocytopenia, Thrombosis, and Systemic Shock
BACKGROUND: Immune complexes (ICs) bind to and activate platelets via FcγRIIA causing patients to experience thrombocytopenia, as well as an increased risk of forming occlusive thrombi. While platelets have been shown to mediate IC-induced pathologies, the mechanisms involved have yet to be fully el...
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| Veröffentlicht in: | J Thromb Haemost |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7831975/ https://ncbi.nlm.nih.gov/pubmed/32767736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.15049 |
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