Ask1 regulates murine platelet granule secretion, thromboxane A(2) generation, and thrombus formation

Mitogen-activated protein kinases (MAPKs) are expressed in platelets and are activated downstream of physiological agonists. Pharmacological and genetic evidence indicate that MAPKs play a significant role in hemostasis and thrombosis, but it is not well understood how MAPKs are activated upon plate...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Naik, Meghna U., Patel, Pravin, Derstine, Randall, Turaga, Ramya, Chen, Xi, Golla, Kalyan, Neeves, Keith B., Ichijo, Hidenori, Naik, Ulhas P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2017
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5374734/
https://ncbi.nlm.nih.gov/pubmed/28028021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-07-729780
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