CD73(+) CD127(high) Long-Term Memory CD4 T Cells Are Highly Proliferative in Response to Recall Antigens and Are Early Targets in HIV-1 Infection

HIV-1 infection rapidly leads to a loss of the proliferative response of memory CD4+ T lymphocytes, when cultured with recall antigens. We report here that CD73 expression defines a subset of resting memory CD4+ T cells in peripheral blood, which highly express the α-chain of the IL-7 receptor (CD12...

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Publicado no:Int J Mol Sci
Main Authors: Seddiki, Nabila, Zaunders, John, Phetsouphanh, Chan, Brezar, Vedran, Xu, Yin, McGuire, Helen M., Bailey, Michelle, McBride, Kristin, Hey-Cunningham, Will, Munier, Cynthia Mee Ling, Cook, Laura, Kent, Stephen, Lloyd, Andrew, Cameron, Barbara, Fazekas de St Groth, Barbara, Koelsch, Kersten, Danta, Mark, Hocini, Hakim, Levy, Yves, Kelleher, Anthony D.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7831934/
https://ncbi.nlm.nih.gov/pubmed/33477692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020912
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