CD4(+) T Follicular Helper and IgA(+) B Cell Numbers in Gut Biopsies from HIV-Infected Subjects on Antiretroviral Therapy Are Similar to HIV-Uninfected Individuals

BACKGROUND: Disruption of gastrointestinal tract epithelial and immune barriers contribute to microbial translocation, systemic inflammation, and progression of HIV-1 infection. Antiretroviral therapy (ART) may lead to reconstitution of CD4(+) T cells in gut-associated lymphoid tissue (GALT), but it...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Zaunders, John, Danta, Mark, Bailey, Michelle, Mak, Gerald, Marks, Katherine, Seddiki, Nabila, Xu, Yin, Templeton, David J., Cooper, David A., Boyd, Mark A., Kelleher, Anthony D., Koelsch, Kersten K.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075890/
https://ncbi.nlm.nih.gov/pubmed/27822211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00438
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