Divergent Expression of CXCR5 and CCR5 on CD4(+) T Cells and the Paradoxical Accumulation of T Follicular Helper Cells during HIV Infection

Viral infection sets in motion a cascade of immune responses, including both CXCR5(+)CD4(+) T follicular helper (Tfh) cells that regulate humoral immunity and CCR5(+)CD4(+) T cells that mediate cell-mediated immunity. In peripheral blood mononuclear cells, the majority of memory CD4(+) T cells appea...

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Bibliographische Detailangaben
Veröffentlicht in:Front Immunol
Hauptverfasser: Zaunders, John, Xu, Yin, Kent, Stephen J., Koelsch, Kersten K., Kelleher, Anthony D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5427074/
https://ncbi.nlm.nih.gov/pubmed/28553284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00495
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