The Majority of HIV Type 1 DNA in Circulating CD4(+) T Lymphocytes Is Present in Non-Gut-Homing Resting Memory CD4(+) T Cells

Memory CD4(+) T lymphocytes in peripheral blood that express integrins α4ß7 preferentially recirculate through gut-associated lymphoid tissue (GALT), a proposed site of significant HIV-1 replication. Tregs and activated CD4(+) T cells in GALT could also be particularly susceptible to infection. We t...

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Detalhes bibliográficos
Main Authors: McBride, Kristin, Xu, Yin, Bailey, Michelle, Seddiki, Nabila, Suzuki, Kazuo, Murray, John M., Gao, Yuan, Yan, Celine, Cooper, David A., Kelleher, Anthony D., Koelsch, Kersten K., Zaunders, John
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3785810/
https://ncbi.nlm.nih.gov/pubmed/23971972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0351
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