Infection of CD127(+) (Interleukin-7 Receptor(+)) CD4(+) Cells and Overexpression of CTLA-4 Are Linked to Loss of Antigen-Specific CD4 T Cells during Primary Human Immunodeficiency Virus Type 1 Infection

We recently found that human immunodeficiency virus (HIV)-specific CD4(+) T cells express coreceptor CCR5 and activation antigen CD38 during early primary HIV-1 infection (PHI) but then rapidly disappear from the circulation. This cell loss may be due to susceptibility to infection with HIV-1 but co...

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Hlavní autoři: Zaunders, John J., Ip, Susanna, Munier, Mee Ling, Kaufmann, Daniel E., Suzuki, Kazuo, Brereton, Choechoe, Sasson, Sarah C., Seddiki, Nabila, Koelsch, Kersten, Landay, Alan, Grey, Pat, Finlayson, Robert, Kaldor, John, Rosenberg, Eric S., Walker, Bruce D., Fazekas de St. Groth, Barbara, Cooper, David A., Kelleher, Anthony D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1617311/
https://ncbi.nlm.nih.gov/pubmed/17005693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00249-06
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