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Alpha-Mangostin Reverses Multidrug Resistance by Attenuating the Function of the Multidrug Resistance-Linked ABCG2 Transporter

The ATP-binding cassette (ABC) drug transporter ABCG2 can actively efflux a wide variety of chemotherapeutic agents out of cancer cells and subsequently reduce the intracellular accumulation of these drugs. Therefore, the overexpression of ABCG2 often contributes to the development of multidrug resi...

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Detaylı Bibliyografya
Yayımlandı:Mol Pharm
Asıl Yazarlar: Wu, Chung-Pu, Hsiao, Sung-Han, Murakami, Megumi, Lu, Yu-Jen, Li, Yan-Qing, Huang, Yang-Hui, Hung, Tai-Ho, Ambudkar, Suresh. V., Wu, Yu-Shan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830752/
https://ncbi.nlm.nih.gov/pubmed/28641010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00334
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