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Alpha-Mangostin Reverses Multidrug Resistance by Attenuating the Function of the Multidrug Resistance-Linked ABCG2 Transporter

The ATP-binding cassette (ABC) drug transporter ABCG2 can actively efflux a wide variety of chemotherapeutic agents out of cancer cells and subsequently reduce the intracellular accumulation of these drugs. Therefore, the overexpression of ABCG2 often contributes to the development of multidrug resi...

詳細記述

保存先:
書誌詳細
出版年:Mol Pharm
主要な著者: Wu, Chung-Pu, Hsiao, Sung-Han, Murakami, Megumi, Lu, Yu-Jen, Li, Yan-Qing, Huang, Yang-Hui, Hung, Tai-Ho, Ambudkar, Suresh. V., Wu, Yu-Shan
フォーマット: Artigo
言語:Inglês
出版事項: 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7830752/
https://ncbi.nlm.nih.gov/pubmed/28641010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.molpharmaceut.7b00334
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