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Tyrphostin RG14620 selectively reverses ABCG2-mediated multidrug resistance in cancer cell lines
The multidrug resistance (MDR) phenotype associated with the overexpression of ATP-binding cassette (ABC) drug transporters ABCB1, ABCC1 and ABCG2 is a major obstacle in cancer chemotherapy. Numerous epidermal growth factor receptor (EGFR) inhibitors have previously been shown capable of reversing M...
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| Udgivet i: | Cancer Lett |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5634936/ https://ncbi.nlm.nih.gov/pubmed/28893612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.08.035 |
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