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SIS3, a specific inhibitor of Smad3 reverses ABCB1- and ABCG2-mediated multidrug resistance in cancer cell lines

One of the major challenges in cancer chemotherapy is the development of multidrug resistance phenomenon attributed to the overexpression of ATP-binding cassette (ABC) transporter ABCB1 or ABCG2 in cancer cells. Therefore, re-sensitizing MDR cancer cells to chemotherapy by directly inhibiting the ac...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Wu, Chung-Pu, Murakami, Megumi, Hsiao, Sung-Han, Liu, Te-Chun, Yeh, Ni, Li, Yan-Qing, Hung, Tai-Ho, Wu, Yu-Shan, Ambudkar, Suresh. V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084781/
https://ncbi.nlm.nih.gov/pubmed/30026175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.07.004
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