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The positive inotropic agent DPI-201106 selectively reverses ABCB1-mediated multidrug resistance in cancer cell lines

The overexpression of ABCB1 in cancer cells is a major factor contributing to the development of multidrug resistance (MDR) and treatment failure in cancer patients. Therefore, re-sensitization of MDR cancer cells to anticancer drugs remains an important aspect in chemotherapy. The progress in devel...

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Detalhes bibliográficos
Publicado no:Cancer Lett
Main Authors: Hsiao, Sung-Han, Murakami, Megumi, Yeh, Ni, Li, Yan-Qing, Hung, Tai-Ho, Wu, Yu-Shan, Ambudkar, Suresh. V., Wu, Chung-Pu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6109596/
https://ncbi.nlm.nih.gov/pubmed/30031116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.07.022
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