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Regulation of Kv11.1 Isoform Expression by Polyadenylate Binding Protein Nuclear 1
The Kv11.1 voltage-gated potassium channel, encoded by the KCNH2 gene, conducts the rapidly activating delayed rectifier current in the heart. KCNH2 pre-mRNA undergoes alternative polyadenylation to generate two C-terminal Kv11.1 isoforms in the heart. Utilization of a poly(A) signal in exon 15 prod...
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| Publicado no: | Int J Mol Sci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7829756/ https://ncbi.nlm.nih.gov/pubmed/33467093 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020863 |
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