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Alternative Splicing and Polyadenylation Contribute to the Generation of hERG1 C-terminal Isoforms

The human ether-a-go-go-related gene 1 (hERG1) encodes the pore-forming subunit of the rapidly activating delayed rectifier potassium channel. Several hERG1 isoforms with different N- and C-terminal ends have been identified. The hERG1a, hERG1b, and hERG1-3.1 isoforms contain the full-length C termi...

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Detalhes bibliográficos
Main Authors: Gong, Qiuming, Stump, Matthew R., Dunn, A. Russell, Deng, Vivianne, Zhou, Zhengfeng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952224/
https://ncbi.nlm.nih.gov/pubmed/20693282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.095695
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