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Upregulation of functional Kv11.1a isoform expression by modified U1 small nuclear RNA

The KCNH2 or human ether-a go-go-related gene (hERG) encodes the Kv11.1 potassium channel that conducts the rapidly activating delayed rectifier potassium current in the heart. The expression of Kv11.1 C-terminal isoforms is directed by the alternative splicing and polyadenylation of intron 9. Splic...

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Foilsithe in:Gene
Main Authors: Gong, Qiuming, Stump, Matthew R., Zhou, Zhengfeng
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5755592/
https://ncbi.nlm.nih.gov/pubmed/29066300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2017.10.063
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