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A Closer Look at Estrogen Receptor Mutations in Breast Cancer and Their Implications for Estrogen and Antiestrogen Responses

Breast cancer (BC) is the most common cancer among women worldwide. More than 70% of BC cases express estrogen receptor alpha (ERα), a central transcription factor that stimulates the proliferation of breast cancer cells, usually in the presence of estrogen. While most cases of ER-positive BC initia...

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Pubblicato in:Int J Mol Sci
Autori principali: Clusan, Léa, Le Goff, Pascale, Flouriot, Gilles, Pakdel, Farzad
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7828590/
https://ncbi.nlm.nih.gov/pubmed/33451133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020756
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