Apigenin, a Partial Antagonist of the Estrogen Receptor (ER), Inhibits ER-Positive Breast Cancer Cell Proliferation through Akt/FOXM1 Signaling

Approximately 80% of breast cancer (BC) cases express the estrogen receptor (ER), and 30–40% of these cases acquire resistance to endocrine therapies over time. Hyperactivation of Akt is one of the mechanisms by which endocrine resistance is acquired. Apigenin (Api), a flavone found in several plant...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Pham, Thu Ha, Page, Yann Le, Percevault, Frédéric, Ferrière, François, Flouriot, Gilles, Pakdel, Farzad
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7796491/
https://ncbi.nlm.nih.gov/pubmed/33466512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22010470
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