Dynamics and competition of CRISPR–Cas9 ribonucleoproteins and AAV donor-mediated NHEJ, MMEJ and HDR editing

Investigations of CRISPR gene knockout editing profiles have contributed to enhanced precision of editing outcomes. However, for homology-directed repair (HDR) in particular, the editing dynamics and patterns in clinically relevant cells, such as human iPSCs and primary T cells, are poorly understoo...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Nucleic Acids Res
Autors principals: Fu, Ya-Wen, Dai, Xin-Yue, Wang, Wen-Tian, Yang, Zhi-Xue, Zhao, Juan-Juan, Zhang, Jian-Ping, Wen, Wei, Zhang, Feng, Oberg, Kerby C, Zhang, Lei, Cheng, Tao, Zhang, Xiao-Bing
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2021
Matèries:
Genome Integrity, Repair and Replication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7826255/
https://ncbi.nlm.nih.gov/pubmed/33398341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa1251
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars