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Intrabodies targeting human papillomavirus 16 E6 and E7 oncoproteins for therapy of established HPV-associated tumors

BACKGROUND: The oncogenic activity of the high risk human papillomavirus type 16 (HPV16) is fully dependent on the E6 and E7 viral oncoproteins produced during viral infection. The oncoproteins interfere with cellular homeostasis by promoting proliferation, inhibiting apoptosis and blocking epitheli...

詳細記述

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書誌詳細
出版年:J Exp Clin Cancer Res
主要な著者: Paolini, Francesca, Amici, Carla, Carosi, Mariantonia, Bonomo, Claudia, Di Bonito, Paola, Venuti, Aldo, Accardi, Luisa
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7825221/
https://ncbi.nlm.nih.gov/pubmed/33485370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-01841-w
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