Molecular Targeting of HuR Oncoprotein Suppresses MITF and Induces Apoptosis in Melanoma Cells

SIMPLE SUMMARY: The human antigen R (HuR) protein regulates the expression of hundreds of proteins in a cell that support tumor growth, drug resistance, and metastases. HuR is overexpressed in several human cancers, including melanoma, and is a molecular target for cancer therapy. Our study objectiv...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Ahmed, Rebaz, Muralidharan, Ranganayaki, Srivastava, Akhil, Johnston, Sarah E., Zhao, Yan D., Ekmekcioglu, Suhendan, Munshi, Anupama, Ramesh, Rajagopal
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7825065/
https://ncbi.nlm.nih.gov/pubmed/33418925
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13020166
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