Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration

BACKGROUND: Human antigen R (HuR) is an RNA binding protein that is overexpressed in many human cancers, including lung cancer, and has been shown to regulate the expression of several oncoproteins. Further, HuR overexpression in cancer cells has been associated with poor-prognosis and therapy resis...

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Detalhes bibliográficos
Publicado no:J Nanobiotechnology
Main Authors: Muralidharan, Ranganayaki, Babu, Anish, Amreddy, Narsireddy, Basalingappa, Kanthesh, Mehta, Meghna, Chen, Allshine, Zhao, Yan Daniel, Kompella, Uday B., Munshi, Anupama, Ramesh, Rajagopal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915183/
https://ncbi.nlm.nih.gov/pubmed/27328938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-016-0201-1
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