Folate receptor-targeted nanoparticle delivery of HuR-RNAi suppresses lung cancer cell proliferation and migration

BACKGROUND: Human antigen R (HuR) is an RNA binding protein that is overexpressed in many human cancers, including lung cancer, and has been shown to regulate the expression of several oncoproteins. Further, HuR overexpression in cancer cells has been associated with poor-prognosis and therapy resis...

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Vydáno v:J Nanobiotechnology
Hlavní autoři: Muralidharan, Ranganayaki, Babu, Anish, Amreddy, Narsireddy, Basalingappa, Kanthesh, Mehta, Meghna, Chen, Allshine, Zhao, Yan Daniel, Kompella, Uday B., Munshi, Anupama, Ramesh, Rajagopal
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4915183/
https://ncbi.nlm.nih.gov/pubmed/27328938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12951-016-0201-1
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