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Ultrasound‐microbubble cavitation facilitates adeno‐associated virus mediated cochlear gene transfection across the round‐window membrane

The round window of the cochlea provides an ideal route for delivering medicines and gene therapy reagents that can cross the round window membrane (RWM) into the inner ear. Recombinant adeno‐associated viruses (rAAVs) have several advantages and are recommended as viral vectors for gene transfectio...

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Detalhes bibliográficos
Publicado no:Bioeng Transl Med
Main Authors: Zhang, Zhen, Chen, Zhengnong, Fan, Liqiang, Landry, Thomas, Brown, Jeremy, Yu, Zhiping, Yin, Shankai, Wang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7823126/
https://ncbi.nlm.nih.gov/pubmed/33532589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/btm2.10189
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