Ultrasound-Mediated Vascular Gene Transfection by Cavitation of Endothelial-Targeted Cationic Microbubbles

OBJECTIVES: Ultrasound-mediated gene delivery can be amplified by acoustic disruption of microbubble carriers that undergo cavitation. We hypothesized that endothelial targeting of microbubbles bearing cDNA is feasible and, through optimizing proximity to the vessel wall, increases the efficacy of g...

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Detalhes bibliográficos
Main Authors: Xie, Aris, Belcik, Todd, Qi, Yue, Morgan, Terry K., Champaneri, Shivam A., Taylor, Sarah, Davidson, Brian P., Zhao, Yan, Klibanov, Alexander L., Kuliszewski, Michael A., Leong-Poi, Howard, Ammi, Azzdine, Lindner, Jonathan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3682923/
https://ncbi.nlm.nih.gov/pubmed/23236976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmg.2012.05.017
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