FLOW AUGMENTATION IN THE MYOCARDIUM BY ULTRASOUND CAVITATION OF MICROBUBBLES: ROLE OF SHEAR-MEDIATED PURINERGIC SIGNALING

BACKGROUND: Ultrasound-mediated cavitation of microbubble contrast agents produces high intravascular shear. We hypothesized that microbubble cavitation increases myocardial microvascular perfusion through shear-dependent purinergic pathways downstream from ATP release that is immediate and sustaine...

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Bibliographic Details
Published in:J Am Soc Echocardiogr
Main Authors: Moccetti, Federico, Belcik, Todd, Latifi, Yllka, Xie, Aris, Ozawa, Koya, Brown, Eran, Davidson, Brian P., Packwood, William, Ammi, Azzdine, Huke, Sabine, Lindner, Jonathan R.
Format: Artigo
Language:Inglês
Published: 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7416478/
https://ncbi.nlm.nih.gov/pubmed/32532642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.echo.2020.03.016
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