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Using Mutability Landscapes To Guide Enzyme Thermostabilization

Thermostabilizing enzymes while retaining their activity and enantioselectivity for applied biocatalysis is an important topic in protein engineering. Rational and computational design strategies as well as directed evolution have been used successfully to thermostabilize enzymes. Herein, we describ...

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Detalhes bibliográficos
Publicado no:Chembiochem
Main Authors: Guo, Chao, Ni, Yan, Biewenga, Lieuwe, Pijning, Tjaard, Thunnissen, Andy‐Mark W. H., Poelarends, Gerrit J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7821111/
https://ncbi.nlm.nih.gov/pubmed/32790123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000442
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