Tissue factor pathway inhibitor is required for cerebrovascular development in mice

Tissue factor pathway inhibitor (TFPI) inhibits proteases in the blood coagulation cascade that lead to the production of thrombin, including prothrombinase (factor Xa [FXa]/FVa), the catalytic complex that directly generates thrombin. Thus, TFPI and FV are directly linked in regulating the procoagu...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Maroney, Susan A., Westrick, Randal J., Cleuren, Audrey C., Martinez, Nicholas D., Siebert, Amy E., Zogg, Mark, Ginsburg, David, Weiler, Hartmut, Mast, Alan E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2021
Assuntos:
Thrombosis and Hemostasis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820871/
https://ncbi.nlm.nih.gov/pubmed/32735640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2020006054
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