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Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway

Pattern recognition receptors (PRRs) are germline-encoded host sensors of the innate immune system. Some human cancer cells have been reported to express PRRs. However, nucleic acid sensors in human cancers have not been studied in detail. Therefore, we systematically analyzed the expression, molecu...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Dev Biol
Prif Awduron: Qiao, Yuan, Zhu, Shan, Deng, Shuanglin, Zou, Shan-Shan, Gao, Bao, Zang, Guoxia, Wu, Jing, Jiang, Yuxue, Liu, Yong-Jun, Chen, Jingtao
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820189/
https://ncbi.nlm.nih.gov/pubmed/33490069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.606001
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