Autoimmunity gene IRGM suppresses cGAS‐STING and RIG‐I‐MAVS signaling to control interferon response

Activation of the type 1 interferon response is extensively connected to the pathogenesis of autoimmune diseases. Loss of function of Immunity Related GTPase M (IRGM) has also been associated to several autoimmune diseases, but its mechanism of action is unknown. Here, we found that IRGM is a master...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:EMBO Rep
Main Authors: Jena, Kautilya Kumar, Mehto, Subhash, Nath, Parej, Chauhan, Nishant Ranjan, Sahu, Rinku, Dhar, Kollori, Das, Saroj Kumar, Kolapalli, Srinivasa Prasad, Murmu, Krushna C, Jain, Ashish, Krishna, Sivaram, Sahoo, Bhabani Sankar, Chattopadhyay, Soma, Rusten, Tor Erik, Prasad, Punit, Chauhan, Swati, Chauhan, Santosh
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2020
Assuntos:
Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7507369/
https://ncbi.nlm.nih.gov/pubmed/32715615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.202050051
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares