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Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway

Pattern recognition receptors (PRRs) are germline-encoded host sensors of the innate immune system. Some human cancer cells have been reported to express PRRs. However, nucleic acid sensors in human cancers have not been studied in detail. Therefore, we systematically analyzed the expression, molecu...

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Bibliographische Detailangaben
Veröffentlicht in:Front Cell Dev Biol
Hauptverfasser: Qiao, Yuan, Zhu, Shan, Deng, Shuanglin, Zou, Shan-Shan, Gao, Bao, Zang, Guoxia, Wu, Jing, Jiang, Yuxue, Liu, Yong-Jun, Chen, Jingtao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820189/
https://ncbi.nlm.nih.gov/pubmed/33490069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.606001
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