Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway

Pattern recognition receptors (PRRs) are germline-encoded host sensors of the innate immune system. Some human cancer cells have been reported to express PRRs. However, nucleic acid sensors in human cancers have not been studied in detail. Therefore, we systematically analyzed the expression, molecu...

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Dettagli Bibliografici
Pubblicato in:Front Cell Dev Biol
Autori principali: Qiao, Yuan, Zhu, Shan, Deng, Shuanglin, Zou, Shan-Shan, Gao, Bao, Zang, Guoxia, Wu, Jing, Jiang, Yuxue, Liu, Yong-Jun, Chen, Jingtao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820189/
https://ncbi.nlm.nih.gov/pubmed/33490069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.606001
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