Runx1 is a central regulator of osteogenesis for bone homeostasis by orchestrating BMP and WNT signaling pathways

Runx1 is highly expressed in osteoblasts, however, its function in osteogenesis is unclear. We generated mesenchymal progenitor-specific (Runx1(f/f)Twist2-Cre) and osteoblast-specific (Runx1(f/f)Col1α1-Cre) conditional knockout (Runx1 CKO) mice. The mutant CKO mice with normal skeletal development d...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:PLoS Genet
Autors principals: Tang, Chen-Yi, Wu, Mengrui, Zhao, Dongfeng, Edwards, Diep, McVicar, Abigail, Luo, Yuan, Zhu, Guochun, Wang, Yongjun, Zhou, Hou-De, Chen, Wei, Li, Yi-Ping
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2021
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819607/
https://ncbi.nlm.nih.gov/pubmed/33476325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1009233
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars