Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response

Endonuclease G (ENDOG), a mitochondrial nuclease, is known to participate in many cellular processes, including apoptosis and paternal mitochondrial elimination, while its role in autophagy remains unclear. Here, we report that ENDOG released from mitochondria promotes autophagy during starvation, w...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Wang, Wenjun, Li, Jianshuang, Tan, Junyang, Wang, Miaomiao, Yang, Jing, Zhang, Zhi-Min, Li, Chuanzhou, Basnakian, Alexei G., Tang, Hong-Wen, Perrimon, Norbert, Zhou, Qinghua
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2021
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817833/
https://ncbi.nlm.nih.gov/pubmed/33473107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20780-2
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker