mTOR Enhances Foam Cell Formation by Suppressing the Autophagy Pathway

Recently, autophagy has drawn more attention in cardiovascular disease as it has important roles in lipid metabolism. Mammalian target of rapamycin (mTOR) is a key regulator of autophagy; however, its effect on atherosclerosis and the underlying mechanism remains undefined. In this study, an obvious...

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Bibliographic Details
Main Authors: Wang, Xiaochuang, Li, Lingxia, Niu, Xiaolin, Dang, Xiaoyan, Li, Ping, Qu, Li, Bi, Xiaoju, Gao, Yanxia, Hu, Yanfen, Li, Manxiang, Qiao, Wanhai, Peng, Zhuo, Pan, Longfei
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2014
Subjects:
Original Research ArticlesOrganelles/Autophagy/Apoptosis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3967384/
https://ncbi.nlm.nih.gov/pubmed/24512183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2013.2164
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