KLF10 Deficiency in CD4(+) T Cells Triggers Obesity, Insulin Resistance, and Fatty Liver

CD4(+) T cells regulate inflammation and metabolism in obesity. An imbalance of CD4(+) T regulatory cells (Tregs) is critical in the development of insulin resistance and diabetes. Although cytokine control of this process is well understood, transcriptional regulation is not. KLF10, a member of the...

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Publicado en:Cell Rep
Autores principales: Wara, Akm Khyrul, Wang, Shijia, Wu, Chun, Fang, Fang, Haemmig, Stefan, Weber, Brittany N., Aydogan, Ceren O., Tesmenitsky, Yevgenia, Aliakbarian, Hassan, Hawse, John R., Subramaniam, Malayannan, Zhao, Lei, Sage, Peter T., Tavakkoli, Ali, Garza, Amanda, Lynch, Lydia, Banks, Alexander S., Feinberg, Mark W.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816773/
https://ncbi.nlm.nih.gov/pubmed/33378664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108550
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