KLF10 Deficiency in CD4(+) T Cells Triggers Obesity, Insulin Resistance, and Fatty Liver

CD4(+) T cells regulate inflammation and metabolism in obesity. An imbalance of CD4(+) T regulatory cells (Tregs) is critical in the development of insulin resistance and diabetes. Although cytokine control of this process is well understood, transcriptional regulation is not. KLF10, a member of the...

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Bibliographic Details
Published in:Cell Rep
Main Authors: Wara, Akm Khyrul, Wang, Shijia, Wu, Chun, Fang, Fang, Haemmig, Stefan, Weber, Brittany N., Aydogan, Ceren O., Tesmenitsky, Yevgenia, Aliakbarian, Hassan, Hawse, John R., Subramaniam, Malayannan, Zhao, Lei, Sage, Peter T., Tavakkoli, Ali, Garza, Amanda, Lynch, Lydia, Banks, Alexander S., Feinberg, Mark W.
Format: Artigo
Language:Inglês
Published: 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816773/
https://ncbi.nlm.nih.gov/pubmed/33378664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108550
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