KLF10 Deficiency in CD4(+) T Cells Triggers Obesity, Insulin Resistance, and Fatty Liver

CD4(+) T cells regulate inflammation and metabolism in obesity. An imbalance of CD4(+) T regulatory cells (Tregs) is critical in the development of insulin resistance and diabetes. Although cytokine control of this process is well understood, transcriptional regulation is not. KLF10, a member of the...

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發表在:Cell Rep
Main Authors: Wara, Akm Khyrul, Wang, Shijia, Wu, Chun, Fang, Fang, Haemmig, Stefan, Weber, Brittany N., Aydogan, Ceren O., Tesmenitsky, Yevgenia, Aliakbarian, Hassan, Hawse, John R., Subramaniam, Malayannan, Zhao, Lei, Sage, Peter T., Tavakkoli, Ali, Garza, Amanda, Lynch, Lydia, Banks, Alexander S., Feinberg, Mark W.
格式: Artigo
語言:Inglês
出版: 2020
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816773/
https://ncbi.nlm.nih.gov/pubmed/33378664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108550
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