Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates

Bile acids are the end products of cholesterol metabolism secreted into bile. They are essential for the absorption of lipids and lipid soluble compounds from the intestine. Here we have identified a series of unusual Δ(5)-unsaturated bile acids in plasma and urine of patients with Smith-Lemli-Opitz...

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Detaylı Bibliyografya
Yayımlandı:J Steroid Biochem Mol Biol
Asıl Yazarlar: Abdel-Khalik, Jonas, Hearn, Thomas, Dickson, Alison L., Crick, Peter J., Yutuc, Eylan, Austin-Muttitt, Karl, Bigger, Brian W., Morris, Andrew A., Shackleton, Cedric H., Clayton, Peter T., Iida, Takashi, Sircar, Ria, Rohatgi, Rajat, Marschall, Hanns-Ulrich, Sjövall, Jan, Björkhem, Ingemar, Mullins, Jonathan G.L., Griffiths, William J., Wang, Yuqin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Pergamon 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7816163/
https://ncbi.nlm.nih.gov/pubmed/33246156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2020.105794
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