Dysregulated follicular regulatory T cells and antibody responses exacerbate experimental autoimmune encephalomyelitis

BACKGROUND: Follicular regulatory T (T(FR)) cells are essential for the regulation of germinal center (GC) response and humoral self-tolerance. Dysregulated follicular helper T (T(FH)) cell-GC-antibody (Ab) response secondary to dysfunctional T(FR) cells is the root of an array of autoimmune disorde...

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Publicado en:J Neuroinflammation
Autores principales: Luo, Lin, Hu, Xianzhen, Dixon, Michael L., Pope, Brandon J., Leavenworth, Jonathan D., Raman, Chander, Meador, William R., Leavenworth, Jianmei W.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2021
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814531/
https://ncbi.nlm.nih.gov/pubmed/33468194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-021-02076-4
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