Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity

AMP-activated protein kinase (AMPK) is an energy sensing metabolic switch in mammalian cells. Here, we report our novel finding that AMPK is lost in all immune cells of experimental autoimmune encephalomyelitis (EAE), an inflammatory disease of Central Nervous System (CNS). AMPKα1 is predominantly e...

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Autors principals: Nath, Narender, Khan, Musfiquidin, Rattan, Ramandeep, Mangalam, Ashutosh, Makkar, Randhir S., de Meester, Carloe, Bertrand, Luc, Singh, Inderjit, Chen, Yingjie, Viollet, Benoit, Giri, Shailendra
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976596/
https://ncbi.nlm.nih.gov/pubmed/19486896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.05.106
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