Loss of AMPK exacerbates experimental autoimmune encephalomyelitis disease severity

AMP-activated protein kinase (AMPK) is an energy sensing metabolic switch in mammalian cells. Here, we report our novel finding that AMPK is lost in all immune cells of experimental autoimmune encephalomyelitis (EAE), an inflammatory disease of Central Nervous System (CNS). AMPKα1 is predominantly e...

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Detalhes bibliográficos
Main Authors: Nath, Narender, Khan, Musfiquidin, Rattan, Ramandeep, Mangalam, Ashutosh, Makkar, Randhir S., de Meester, Carloe, Bertrand, Luc, Singh, Inderjit, Chen, Yingjie, Viollet, Benoit, Giri, Shailendra
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976596/
https://ncbi.nlm.nih.gov/pubmed/19486896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.05.106
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